Amoxicillin-clavulanate potassium

For research use only. Not for therapeutic Use.

  • CAT Number: R037133
  • CAS Number: 74469-00-4
  • Molecular Formula: C24H27KN4O10S
  • Molecular Weight: 602.66
  • Purity: ≥95%
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Amoxicillin-clavulanate potassium(Cat No.:R037133)is a broad-spectrum beta-lactam/beta-lactamase inhibitor combination antibiotic, composed of amoxicillin, a penicillin-class antibiotic, and clavulanate potassium, a beta-lactamase inhibitor. Amoxicillin inhibits bacterial cell wall synthesis, while clavulanate blocks beta-lactamase enzymes that confer resistance, thereby extending the drug’s efficacy against beta-lactamase–producing bacteria. This combination is widely used to treat respiratory tract infections, urinary tract infections, skin infections, and sinusitis caused by Gram-positive and Gram-negative pathogens. It is available in both oral and intravenous formulations, offering broad clinical utility and a well-established safety profile in community and hospital settings.


CAS Number 74469-00-4
Synonyms

potassium;(2S,5R,6R)-6-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;(2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylate

Molecular Formula C24H27KN4O10S
Purity ≥95%
IUPAC Name potassium;(2S,5R,6R)-6-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;(2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylate
InChI InChI=1S/C16H19N3O5S.C8H9NO5.K/c1-16(2)11(15(23)24)19-13(22)10(14(19)25-16)18-12(21)9(17)7-3-5-8(20)6-4-7;10-2-1-4-7(8(12)13)9-5(11)3-6(9)14-4;/h3-6,9-11,14,20H,17H2,1-2H3,(H,18,21)(H,23,24);1,6-7,10H,2-3H2,(H,12,13);/q;;+1/p-1/b;4-1-;/t9-,10-,11+,14-;6-,7-;/m11./s1
InChIKey DWHGNUUWCJZQHO-ZVDZYBSKSA-M
SMILES CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=C(C=C3)O)N)C(=O)O)C.C1[C@@H]2N(C1=O)[C@H](/C(=C/CO)/O2)C(=O)[O-].[K+]
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