Amorolfine HCl

• CAT Number: A000580
• CAS Number: 78613-38-4
• Molecular Formula: C21H36ClNO
• Molecular Weight: 353.97
• Purity: ≥95%
• Target: Antibiotic
• Solubility: >6.3mg/mL in DMSO
• Storage: 3 years -20C powder
• IUPAC Name: (2R,6S)-2,6-dimethyl-4-[2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl]morpholine;hydrochloride
• InChI: InChI=1S/C21H35NO.ClH/c1-7-21(5,6)20-10-8-19(9-11-20)12-16(2)13-22-14-17(3)23-18(4)15-22;/h8-11,16-18H,7,12-15H2,1-6H3;1H/t16?,17-,18+
• InChIKey: XZKWIPVTHGWDCF-KUZYQSSXSA-N
• SMILES: CC(C1=CC=C(CC(C)CN2C[C@@H](C)O[C@@H](C)C2)C=C1)(C)CC.[H]Cl

Amorolfine HCl (CAS 78613-38-4) is a 14-alpha demethylase inhibitor that inhibits ergosterol synthesis and fungal cell wall formation. In also increases release for prostaglandin D2 metabolites and inhibits production of thymic stromal lymphopoietin in dermatitis models.

Reference

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