For research use only. Not for therapeutic Use.
Amodiaquine（Cat No.:R004836）is a 4-aminoquinoline antimalarial drug structurally related to chloroquine, widely used in the treatment and prevention of Plasmodium falciparum malaria. It acts by inhibiting heme detoxification within the parasite’s food vacuole, leading to toxic heme accumulation and parasite death. Amodiaquine is often administered in combination therapies, such as with artesunate, to enhance efficacy and reduce resistance. Beyond malaria, it has been investigated for antiviral and anti-inflammatory properties. Researchers employ amodiaquine in pharmacology, tropical medicine, and drug-resistance studies to develop improved therapeutic strategies.
| CAS Number | 86-42-0 |
| Synonyms | 4-[(7-chloroquinolin-4-yl)amino]-2-(diethylaminomethyl)phenol |
| Molecular Formula | C20H22ClN3O |
| Purity | ≥95% |
| IUPAC Name | 4-[(7-chloroquinolin-4-yl)amino]-2-(diethylaminomethyl)phenol |
| InChI | InChI=1S/C20H22ClN3O/c1-3-24(4-2)13-14-11-16(6-8-20(14)25)23-18-9-10-22-19-12-15(21)5-7-17(18)19/h5-12,25H,3-4,13H2,1-2H3,(H,22,23) |
| InChIKey | OVCDSSHSILBFBN-UHFFFAOYSA-N |
| SMILES | CCN(CC)CC1=C(C=CC(=C1)NC2=C3C=CC(=CC3=NC=C2)Cl)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
