Amino-PEG5-CH2COOH

• CAT Number: I014108
• CAS Number: 141282-35-1
• Molecular Formula: C12H25NO7
• Molecular Weight: 295.33
• Purity: ≥95%
• Synonyms: 2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid
• InChI: InChI=1S/C12H25NO7/c13-1-2-16-3-4-17-5-6-18-7-8-19-9-10-20-11-12(14)15/h1-11,13H2,(H,14,15)
• InChIKey: ZQGSSZVORHCAFC-UHFFFAOYSA-N
• SMILES: C(COCCOCCOCCOCCOCC(=O)O)N

Amino-PEG5-CH2COOH(CAT: I014108) is a heterobifunctional polyethylene glycol (PEG) linker featuring a primary amine at one end and a carboxylic acid at the other, separated by a five-unit PEG spacer. The amine group enables coupling to activated esters, isothiocyanates, or aldehydes, while the carboxyl group allows conjugation with amines through amide bond formation. The PEG5 spacer enhances hydrophilicity, flexibility, and solubility, while reducing steric hindrance in conjugation reactions. Amino-PEG5-CH2COOH is widely used in bioconjugation, drug delivery, PEGylation, and surface functionalization, serving as a versatile building block for constructing multifunctional biomolecules, polymers, and nanostructures with improved stability and biocompatibility.