Amifostine

• CAT Number: I002582
• CAS Number: 20537-88-6
• Molecular Formula: C5H15N2O3PS
• Molecular Weight: 214.22
• Purity: ≥95%
• Target: Metabolic Enzyme/Protease
• Solubility: H2O: ＞ 40 mg/mL
• Storage: Store at -20°C
• IUPAC Name: 2-(3-aminopropylamino)ethylsulfanylphosphonic acid
• InChI: InChI=1S/C5H15N2O3PS/c6-2-1-3-7-4-5-12-11(8,9)10/h7H,1-6H2,(H2,8,9,10)
• InChIKey: JKOQGQFVAUAYPM-UHFFFAOYSA-N
• SMILES: C(CN)CNCCSP(=O)(O)O

Amifostine(CAT: I002582) is a cytoprotective agent widely utilized in cancer research for its ability to mitigate the harmful effects of chemotherapy and radiation therapy on healthy tissues. Acting as a prodrug, it is converted into an active thiol metabolite that protects normal cells from oxidative damage and DNA injury. Amifostine plays a critical role in oncology research by offering insights into mechanisms of cellular protection, reducing side effects, and enhancing the therapeutic index of cancer treatments. Its versatility makes it a valuable tool for developing strategies to improve patient outcomes in cancer therapy.