Amifampridine

For research use only. Not for therapeutic Use.

  • CAT Number: I004036
  • CAS Number: 54-96-6
  • Molecular Formula: C5H7N3
  • Molecular Weight: 109.13
  • Purity: 98%
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Amifampridine(Cat No.:I004036)is a potassium channel blocker used to treat Lambert-Eaton myasthenic syndrome (LEMS), a rare autoimmune disorder that affects the neuromuscular junction. By blocking voltage-gated potassium channels, Amifampridine prolongs the duration of action potentials, enhancing the release of acetylcholine at nerve terminals. This improves muscle strength and reduces symptoms such as muscle weakness and fatigue. Amifampridine has shown efficacy in improving motor function and quality of life for patients with LEMS, offering a targeted therapy for managing the symptoms of this challenging neuromuscular condition.


Catalog Number I004036
CAS Number 54-96-6
Molecular Formula C5H7N3
Purity 98%
Target Potassium Channel
Target Protein

Q09470

Solubility DMSO: ≥ 38 mg/mL
Appearance Solid
Storage Dry, dark and at 2 - 8 °C for six months or -20°C for two years.
IUPAC Name pyridine-3,4-diamine
InChI InChI=1S/C5H7N3/c6-4-1-2-8-3-5(4)7/h1-3H,7H2,(H2,6,8)
InChIKey OYTKINVCDFNREN-UHFFFAOYSA-N
SMILES C1=CN=CC(=C1N)N
Reference

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<br>[1]. http://en.wikipedia.org/wiki/3,4-Diaminopyridine#cite_note-4
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