AMD-070 (AMD11070) - CAS 558447-26-0

AMD070 (CAT: I001988), also known as AMD11070, is a potent and orally bioavailable inhibitor of the chemokine receptor CXCR4. CXCR4 is a receptor involved in cell migration and plays a critical role in various physiological and pathological processes, including cancer metastasis, HIV infection, and inflammatory diseases. By inhibiting CXCR4, AMD070 blocks the interaction between CXCR4 and its ligand, CXCL12, thereby disrupting signaling pathways associated with cell migration and invasion. AMD070 has shown promise as a therapeutic agent in preclinical studies and is being investigated for its potential applications in the treatment of cancer and other diseases where CXCR4 signaling is dysregulated.

Catalog Number: I001988

CAS Number: 558447-26-0

PubChem Substance ID:355040215

Molecular Formula: C21H27N5

Molecular Weight:348.48

Purity: ≥95%

* For research use only. Not for human or veterinary use.


SynonymsAMD11070; AMD-11070; AMD 11070; AMD-070; AMD 070; AMD070.;(S)-N1-((1H-benzo[d]imidazol-2-yl)methyl)-N1-(5,6,7,8-tetrahydroquinolin-8-yl)butane-1,4-diamine


Molecular Formula: C21H27N5
Molecular Weight348.48
Target:CXCR4 inhibitor
SolubilitySoluble in DMSO, not in water
Storage0 - 4°Cfor short term (days to weeks), or -20 °C for long term (months).
Related CAS.880549-30-4(hydrochloride)

Computed Descriptor