For research use only. Not for therapeutic Use.
Altanserin (Cat No.: R072237) is a potent and selective serotonin 5-HT2A receptor antagonist widely used in neuropharmacology and brain imaging studies. It has been employed as a radioligand in positron emission tomography (PET) to map 5-HT2A receptor distribution in the human brain, aiding research into psychiatric and neurological disorders. Altanserin provides valuable insights into the role of serotonin signaling in depression, schizophrenia, and anxiety. Its high receptor selectivity and radiolabeling potential make it a crucial tool in neuroscience and drug discovery.
| CAS Number | 76330-71-7 |
| Synonyms | 3-[2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl]-2-sulfanylidene-1H-quinazolin-4-one |
| Molecular Formula | C22H22FN3O2S |
| Purity | ≥95% |
| InChI | InChI=1S/C22H22FN3O2S/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29/h1-8,16H,9-14H2,(H,24,29) |
| InChIKey | SMYALUSCZJXWHG-UHFFFAOYSA-N |
| SMILES | C1CN(CCC1C(=O)C2=CC=C(C=C2)F)CCN3C(=O)C4=CC=CC=C4NC3=S |
| Reference | [1]. Biver F, et al. Multicompartmental study of fluorine-18 altanserin binding to brain 5HT2 receptors in humans using positron emission tomography. Eur J Nucl Med. 1994;21(9):937-946. |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
