For research use only. Not for therapeutic Use.
ALPK1-IN-1（Cat No.:I043511）is a selective inhibitor of ALPK1 (applied in liver kinase B1), an enzyme involved in the regulation of cellular stress responses, immunity, and inflammation. ALPK1 plays a role in innate immunity by sensing and responding to bacterial infections and cellular damage. By inhibiting ALPK1, ALPK1-IN-1 may help modulate these pathways, offering potential therapeutic benefits in diseases driven by excessive inflammation or immune responses, such as autoimmune disorders or chronic inflammatory conditions. Ongoing research is focused on evaluating its efficacy and safety for therapeutic use in inflammatory and immune-related diseases.
| CAS Number | 2765457-72-3 |
| Synonyms | 1-[4-[2-(4-methoxyphenyl)propan-2-yl]-1,3-thiazol-2-yl]-3-[1-(6-piperazin-1-ylpyridin-3-yl)ethyl]urea |
| Molecular Formula | C25H32N6O2S |
| Purity | ≥95% |
| IUPAC Name | 1-[4-[2-(4-methoxyphenyl)propan-2-yl]-1,3-thiazol-2-yl]-3-[1-(6-piperazin-1-ylpyridin-3-yl)ethyl]urea |
| InChI | InChI=1S/C25H32N6O2S/c1-17(18-5-10-22(27-15-18)31-13-11-26-12-14-31)28-23(32)30-24-29-21(16-34-24)25(2,3)19-6-8-20(33-4)9-7-19/h5-10,15-17,26H,11-14H2,1-4H3,(H2,28,29,30,32) |
| InChIKey | JWNGYFWRZVKHOW-UHFFFAOYSA-N |
| SMILES | CC(C1=CN=C(C=C1)N2CCNCC2)NC(=O)NC3=NC(=CS3)C(C)(C)C4=CC=C(C=C4)OC |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
