ABTL0812 (Cat No.:I013350), also known as α-Hydroxylinoleic acid, LP-10218, SCLN-0812, can inhibit the Akt/mTOR axis by inducing the overexpression of TRIB3 and activating autophagy in lung squamous cell carcinoma cell lines. ABTL0812 also induces AMPK activation and ROS accumulation.
| Catalog Number | I013350 |
| CAS Number | 57818-44-7 |
| Molecular Formula | C₁₈H₃₂O₃ |
| Purity | 95% |
| Target | mTOR |
| Solubility | DMSO |
| Storage | Store at -20°C |
| IUPAC Name | (9Z,12Z)-2-hydroxyoctadeca-9,12-dienoic acid |
| InChI | InChI=1S/C18H32O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17(19)18(20)21/h6-7,9-10,17,19H,2-5,8,11-16H2,1H3,(H,20,21)/b7-6-,10-9- |
| InChIKey | AFDSETGKYZMEEA-HZJYTTRNSA-N |
| SMILES | CCCCCC=CCC=CCCCCCCC(C(=O)O)O |
