Allo-aca

• CAT Number: I044196
• Molecular Formula: C48H75N13O15
• Molecular Weight: 1074.19
• Purity: ≥95%
• Synonyms: (4S)-4-[[(2S,3S)-2-amino-3-hydroxybutanoyl]amino]-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[4-(2-amino-2-oxoethyl)-2-oxochromen-7-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopentan-2-yl]amino]-5-oxopentanoic acid
• InChI: InChI=1S/C48H75N13O15/c1-8-10-29(56-42(70)31(14-15-36(65)66)58-46(74)38(50)25(7)63)43(71)61-39(23(4)5)47(75)54-24(6)40(68)59-32(17-22(2)3)44(72)60-33(21-62)45(73)57-30(11-9-16-53-48(51)52)41(69)55-27-12-13-28-26(18-35(49)64)19-37(67)76-34(28)20-27/h12-13,19-20,22-25,29-33,38-39,62-63H,8-11,14-18,21,50H2,1-7H3,(H2,49,64)(H,54,75)(H,55,69)(H,56,70)(H,57,73)(H,58,74)(H,59,68)(H,60,72)(H,61,71)(H,65,66)(H4,51,52,53)/t24-,25-,29-,30-,31-,32-,33-,38-,39-/m0/s1
• InChIKey: HBIZXCPYXWQUEB-PPHQEZGGSA-N
• SMILES: CCC[C@@H](C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NC1=CC2=C(C=C1)C(=CC(=O)O2)CC(=O)N)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H]([C@H](C)O)N

Allo-aca（Cat No.:I044196）is a synthetic peptide antagonist of the melanocortin-1 receptor (MC1R), derived from the α-melanocyte-stimulating hormone (α-MSH) analogs. It functions by selectively blocking MC1R signaling, which plays a key role in melanogenesis, inflammation, and immune regulation. Allo-aca has been studied for its potential to modulate pigmentation, reduce inflammation, and regulate energy balance. Its stability and receptor specificity make it a valuable tool for probing melanocortin pathways in dermatological, metabolic, and neuroinflammatory research. Researchers also explore its therapeutic applications in conditions like melanoma, obesity, and inflammatory skin disorders.