For research use only. Not for therapeutic Use.
ALK Kinase Inhibitor-1（Cat No.:I036002）is a selective small-molecule inhibitor targeting anaplastic lymphoma kinase (ALK), a receptor tyrosine kinase implicated in various cancers, including non-small cell lung cancer (NSCLC), anaplastic large cell lymphoma, and neuroblastoma. By blocking ALK phosphorylation and downstream signaling pathways, this inhibitor suppresses tumor cell proliferation, survival, and metastasis. ALK Kinase Inhibitor-1 is widely used in preclinical and cellular studies to evaluate ALK-driven oncogenic mechanisms and therapeutic response. Its specificity and potency make it a valuable tool in cancer research and the development of targeted therapies against ALK-positive malignancies.
| CAS Number | 1462949-64-9 |
| Synonyms | [7-(5-fluoro-2-methoxyphenyl)-2-[4-(4-methylpiperazin-1-yl)-2-propan-2-yloxyanilino]thieno[3,2-d]pyrimidin-6-yl]methanol |
| Molecular Formula | C28H32FN5O3S |
| Purity | ≥95% |
| IUPAC Name | [7-(5-fluoro-2-methoxyphenyl)-2-[4-(4-methylpiperazin-1-yl)-2-propan-2-yloxyanilino]thieno[3,2-d]pyrimidin-6-yl]methanol |
| InChI | InChI=1S/C28H32FN5O3S/c1-17(2)37-23-14-19(34-11-9-33(3)10-12-34)6-7-21(23)31-28-30-15-24-27(32-28)26(25(16-35)38-24)20-13-18(29)5-8-22(20)36-4/h5-8,13-15,17,35H,9-12,16H2,1-4H3,(H,30,31,32) |
| InChIKey | SWRGFJBGNAEJOY-UHFFFAOYSA-N |
| SMILES | CC(C)OC1=C(C=CC(=C1)N2CCN(CC2)C)NC3=NC=C4C(=N3)C(=C(S4)CO)C5=C(C=CC(=C5)F)OC |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
