ALDEHYDE DEHYDROGENASE

• CAT Number: M015142
• CAS Number: 9028-88-0
• Molecular Formula: NULL
• Purity: ≥95%
• Synonyms: EC 1.2.1.5;EC: 1.2.1.5;ADH;ALDEHYDE DEHYDROGENASE;ALDEHYDE DEHYDROGENASE, POTASSIUM-ACTIVATED BAKER/’S YEAST (S CEREVISIAE);ALDEHYDE DEHYDROGENASE, YEAST;ALDEHYDE NAD(P)+ OXIDOREDUCTASE;ALDEHYDE: NAD (P) + OXIDOREDUCTASE
• Target: Aldehyde Dehydrogenase (ALDH)
• Storage: Store at -20°C

Aldehyde dehydrogenase (Cat No.:M015142) is a family of enzymes that catalyze the oxidation of aldehydes to their corresponding carboxylic acids using NAD⁺ or NADP⁺ as a cofactor. Found in various tissues across species, ALDH plays a crucial role in detoxifying endogenous and exogenous aldehydes, including those from alcohol metabolism (e.g., acetaldehyde). It is vital for cellular homeostasis, protecting against oxidative stress and toxic intermediates. Genetic variants, particularly in ALDH2, can affect alcohol tolerance and disease susceptibility. ALDH enzymes are also studied for their roles in cancer, stem cell biology, and drug resistance.