Albendazole sulfone

• CAT Number: R002787
• CAS Number: 75184-71-3
• Molecular Formula: C12H15N3O4S
• Molecular Weight: 297.33
• Purity: ≥95%
• Synonyms: methyl N-(6-propylsulfonyl-1H-benzimidazol-2-yl)carbamate
• InChI: InChI=1S/C12H15N3O4S/c1-3-6-20(17,18)8-4-5-9-10(7-8)14-11(13-9)15-12(16)19-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)
• InChIKey: CLSJYOLYMZNKJB-UHFFFAOYSA-N
• SMILES: CCCS(=O)(=O)C1=CC2=C(C=C1)N=C(N2)NC(=O)OC

Albendazole sulfone（Cat No.:R002787）is a primary metabolite of albendazole, a broad-spectrum anthelmintic agent used to treat parasitic worm infections. This sulfone derivative results from further oxidation of albendazole sulfoxide and retains antiparasitic activity by disrupting microtubule formation through binding to β-tubulin. It inhibits glucose uptake and depletes glycogen stores in helminths, leading to energy starvation and parasite death. Albendazole sulfone is valuable in pharmacokinetic and metabolic studies, helping to assess drug efficacy, bioavailability, and safety profiles in both preclinical and clinical research contexts.