AG-09/1

• CAT Number: I015316
• CAS Number: 356776-32-4
• Molecular Formula: C16H14N4O4S
• Molecular Weight: 358.37
• Purity: ≥95%
• Synonyms: 2-[(6-methoxy-1H-benzimidazol-2-yl)sulfanyl]-N-(4-nitrophenyl)acetamide
• InChI: InChI=1S/C16H14N4O4S/c1-24-12-6-7-13-14(8-12)19-16(18-13)25-9-15(21)17-10-2-4-11(5-3-10)20(22)23/h2-8H,9H2,1H3,(H,17,21)(H,18,19)
• InChIKey: LYQDSNOFTIZWAX-UHFFFAOYSA-N
• SMILES: COC1=CC2=C(C=C1)N=C(N2)SCC(=O)NC3=CC=C(C=C3)[N+](=O)[O-]

AG-09/1（Cat No.:I015316）is a synthetic small-molecule inhibitor designed to target angiogenesis-related pathways. It exhibits potent anti-proliferative and anti-migratory effects on endothelial cells, thereby interfering with new blood vessel formation. Through modulation of VEGF-mediated signaling and related pathways, AG-09/1 shows promise in suppressing tumor vascularization and growth. Its mechanism highlights therapeutic potential in oncology research, particularly for cancers reliant on angiogenesis for progression. Beyond oncology, AG-09/1 serves as a valuable probe in studying vascular biology, angiogenic mechanisms, and the development of next-generation anti-angiogenic therapeutics.