For research use only. Not for therapeutic Use.
AEF0117(CAT: I040535) is a signaling-specific inhibitor (SSi) of the cannabinoid receptor type 1 (CB1), designed to selectively modulate receptor activity without blocking endogenous cannabinoid binding. By targeting intracellular signaling pathways downstream of CB1, AEF0117 attenuates the psychoactive and reinforcing effects of Δ⁹-THC while preserving normal physiological functions of the endocannabinoid system. This unique mechanism makes AEF0117 a promising therapeutic candidate for Cannabis Use Disorder (CUD), offering behavioral and neurochemical modulation without inducing withdrawal or intoxication. AEF0117 is ideal for research in neuropharmacology, addiction biology, and cannabinoid receptor signaling. Supplied in high purity for advanced biomedical and translational studies.
| CAS Number | 1610878-71-1 |
| Synonyms | 1-[(3S,8S,9S,10R,13S,14S,17S)-3-[(4-methoxyphenyl)methoxy]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone |
| Molecular Formula | C29H40O3 |
| Purity | ≥95% |
| IUPAC Name | 1-[(3S,8S,9S,10R,13S,14S,17S)-3-[(4-methoxyphenyl)methoxy]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone |
| InChI | InChI=1S/C29H40O3/c1-19(30)25-11-12-26-24-10-7-21-17-23(32-18-20-5-8-22(31-4)9-6-20)13-15-28(21,2)27(24)14-16-29(25,26)3/h5-9,23-27H,10-18H2,1-4H3/t23-,24-,25+,26-,27-,28-,29+/m0/s1 |
| InChIKey | AAZPIQPULVRHOW-SFKJMYEFSA-N |
| SMILES | CC(=O)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OCC5=CC=C(C=C5)OC)C)C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
