Adrenocorticotropic hormone TFA

• CAT Number: I042372
• Molecular Formula: C207H308N56O58S.xC2HF3O2
• Molecular Weight: 4541.14 (free base)
• Purity: ≥95%

Adrenocorticotropic hormone TFA (ACTH TFA salt) (Cat No.: I042372) is a synthetic or purified form of ACTH presented as a trifluoroacetate salt. ACTH is a polypeptide hormone produced by the anterior pituitary that stimulates the adrenal cortex to secrete glucocorticoids, particularly cortisol. It plays a crucial role in the hypothalamic-pituitary-adrenal (HPA) axis, regulating stress response, immune modulation, and metabolism. The TFA form enhances stability for research and pharmaceutical applications, including studies on endocrine disorders, adrenal function, and corticosteroid-related drug development.

Reference

[1]. Houngbadji MSTS, et al. Syndrome de résistance à l’Adrénocorticotrophine Hormone (ACTH): à propos d’un cas [Adrenocorticotropic hormone (ACTH) insensitivity syndrome: about a case]. Pan Afr Med J. 2018 Aug 2;30:244. French.
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[2]. Campbell I, et al. The effect of adrenocorticotrophic hormone on the yield, composition and butterfat properties of cow’s milk. Journal of Dairy Research. 1964, 31(1), 71-79.