For research use only. Not for therapeutic Use.
Aderamastat (FP-025)(CAT: I040525) is an orally active, selective inhibitor of matrix metalloproteinase-12 (MMP-12), an enzyme implicated in tissue remodeling, inflammation, and extracellular matrix degradation. By targeting MMP-12, Aderamastat modulates key pathological processes involved in chronic respiratory diseases. It has shown therapeutic potential in the treatment of asthma, chronic obstructive pulmonary disease (COPD), and pulmonary fibrosis by reducing airway inflammation, improving lung function, and limiting fibrotic tissue buildup. Aderamastat is a valuable research tool for studying the role of MMP-12 in pulmonary disease progression and for developing targeted interventions in inflammatory and fibrotic respiratory conditions. Suitable for preclinical and translational studies.
| CAS Number | 877176-23-3 |
| Synonyms | 5-[3-[4-[(3-methylphenyl)methoxy]phenyl]sulfanylfuran-2-yl]imidazolidine-2,4-dione |
| Molecular Formula | C21H18N2O4S |
| Purity | ≥95% |
| IUPAC Name | 5-[3-[4-[(3-methylphenyl)methoxy]phenyl]sulfanylfuran-2-yl]imidazolidine-2,4-dione |
| InChI | InChI=1S/C21H18N2O4S/c1-13-3-2-4-14(11-13)12-27-15-5-7-16(8-6-15)28-17-9-10-26-19(17)18-20(24)23-21(25)22-18/h2-11,18H,12H2,1H3,(H2,22,23,24,25) |
| InChIKey | CXEKSVVDMIAMLF-UHFFFAOYSA-N |
| SMILES | CC1=CC(=CC=C1)COC2=CC=C(C=C2)SC3=C(OC=C3)C4C(=O)NC(=O)N4 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
