Adenosine 5′-monophosphoramidate sodium

• CAT Number: R050118
• CAS Number: 102029-68-5
• Molecular Formula: C10H14N6NaO6P
• Molecular Weight: 368.22
• Purity: ≥95%
• Synonyms: sodium;amino-[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy]phosphinate
• InChI: InChI=1S/C10H15N6O6P.Na/c11-8-5-9(14-2-13-8)16(3-15-5)10-7(18)6(17)4(22-10)1-21-23(12,19)20;/h2-4,6-7,10,17-18H,1H2,(H2,11,13,14)(H3,12,19,20);/q;+1/p-1/t4-,6-,7-,10-;/m1./s1
• InChIKey: ALRHXZAMLVPXPL-MCDZGGTQSA-M
• SMILES: C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(N)[O-])O)O)N.[Na+]

Adenosine 5′-monophosphoramidate sodium（Cat No.:R050118）is a synthetic nucleotide analog derived from adenosine monophosphate (AMP), in which the phosphate group is modified with an amidate linkage. This structural modification alters its enzymatic recognition and stability, making it a useful tool in biochemical and pharmacological studies. It has been applied in research to investigate nucleotide metabolism, enzyme-substrate specificity, and signal transduction pathways involving purine nucleotides. The sodium salt form improves solubility and handling, supporting its use in enzymology, molecular biology, and drug discovery focused on nucleotide-related therapeutic targets.