Acriflavine hydrochloride

• CAT Number: I044731
• CAS Number: 69235-50-3
• Molecular Formula: C27H27Cl3N6
• Molecular Weight: 541.90
• Purity: ≥95%
• Synonyms: acridine-3,6-diamine;10-methylacridin-10-ium-3,6-diamine;chloride;dihydrochloride
• IUPAC Name: acridine-3,6-diamine;10-methylacridin-10-ium-3,6-diamine;chloride;trihydrochloride
• InChI: InChI=1S/C14H13N3.C13H11N3.4ClH/c1-17-13-7-11(15)4-2-9(13)6-10-3-5-12(16)8-14(10)17;14-10-3-1-8-5-9-2-4-11(15)7-13(9)16-12(8)6-10;;;;/h2-8H,1H3,(H3,15,16);1-7H,14-15H2;4*1H
• InChIKey: VWXAJKFSYJFBIW-UHFFFAOYSA-N
• SMILES: C[N+]1=C2C=C(C=CC2=CC3=C1C=C(C=C3)N)N.C1=CC(=CC2=NC3=C(C=CC(=C3)N)C=C21)N.Cl.Cl.Cl.[Cl-]

Acriflavine hydrochloride（Cat No.:I044731）is an antiseptic and fluorescent dye composed of a mixture of proflavine and trypaflavine. It is widely used for its antimicrobial properties, particularly against bacteria, fungi, and some viruses. As a topical antiseptic, it is applied to wounds, burns, and skin infections. In research, acriflavine serves as a fluorescent probe and a DNA intercalating agent, useful in molecular biology studies. Additionally, it has been investigated for its potential to inhibit hypoxia-inducible factor-1 (HIF-1), making it of interest in cancer and anti-angiogenic research.