Acid-PEG4-S-S-PEG4-acid

• CAT Number: I016124
• CAS Number: 2055015-40-0
• Molecular Formula: C22H42O12S2
• Molecular Weight: 562.69
• Purity: ≥95%
• Synonyms: 3-[2-[2-[2-[2-[2-[2-[2-[2-(2-carboxyethoxy)ethoxy]ethoxy]ethoxy]ethyldisulfanyl]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
• InChI: InChI=1S/C22H42O12S2/c23-21(24)1-3-27-5-7-29-9-11-31-13-15-33-17-19-35-36-20-18-34-16-14-32-12-10-30-8-6-28-4-2-22(25)26/h1-20H2,(H,23,24)(H,25,26)
• InChIKey: GRXXQSGPDQBZKA-UHFFFAOYSA-N
• SMILES: C(COCCOCCOCCOCCSSCCOCCOCCOCCOCCC(=O)O)C(=O)O

Acid-PEG4-S-S-PEG4-acid（Cat No.:I016124）is a symmetric, cleavable linker featuring terminal carboxylic acid groups for versatile conjugation with amines and other reactive species. Its PEG4 spacers enhance solubility, flexibility, and biocompatibility, while minimizing steric hindrance in biomolecule or polymer modifications. The central disulfide (S-S) bond provides a redox-sensitive cleavage site, enabling controlled release under reducing conditions. This balanced design makes the linker highly useful in drug delivery systems, antibody–drug conjugates, polymer conjugates, and chemical biology research where stability, solubility, and triggered release are essential for targeted applications.