Acid Ceramidase-IN-1

• CAT Number: I045229
• CAS Number: 2415225-30-6
• Molecular Formula: C18H25N3O3
• Molecular Weight: 331.41
• Purity: ≥95%
• Synonyms: 6-(1-methylpiperidin-4-yl)-N-(2-methylpropyl)-2-oxo-1,3-benzoxazole-3-carboxamide
• InChI: InChI=1S/C18H25N3O3/c1-12(2)11-19-17(22)21-15-5-4-14(10-16(15)24-18(21)23)13-6-8-20(3)9-7-13/h4-5,10,12-13H,6-9,11H2,1-3H3,(H,19,22)
• InChIKey: AYXQGWOLRJUITD-UHFFFAOYSA-N
• SMILES: CC(C)CNC(=O)N1C2=C(C=C(C=C2)C3CCN(CC3)C)OC1=O

Acid Ceramidase‑IN‑1（Cat No.:I045229）is a potent, orally bioavailable inhibitor of acid ceramidase (AC, also known as ASAH‑1), with a human AC IC₅₀ of approximately 0.166 µM. It exhibits excellent brain penetration in mice, making it a useful probe for neurological disease research. The compound has a molecular weight of 331.41 (C₁₈H₂₅N₃O₃) and is supplied as a high‑purity solid (≥99 %). Acid Ceramidase-IN-1 offers researchers a valuable tool for studying sphingolipid metabolism and ceramidase-related pathways in both central nervous system and metabolic disease contexts.