Acetyl tetrapeptide-9

  • CAT Number: I021281
  • CAS Number: 928006-50-2
  • Molecular Formula: C22H33N7O9
  • Molecular Weight: 539.54
  • Purity: 98%
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Acetyl tetrapeptide-9(CAT: I021281) is a peptide compound that has been studied for its potential role in skincare and cosmetics. It is believed to play a role in stimulating the production of basement membrane polysaccharide (lumican) and collagen type I synthesis. These activities suggest that Acetyl tetrapeptide-9 may have applications in promoting skin health and elasticity, potentially contributing to anti-aging effects. It is commonly used as an ingredient in cosmetic formulations aimed at improving skin appearance and texture.

Catalog Number I021281
CAS Number 928006-50-2

Acetyl tetrapeptide-9; LS 9745; LS-9745; LS9745; N-Acetyl-gln-asp-val-his; Dermican;

Molecular Formula


Purity 98
Solubility Soluble in DMSO
Storage Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
IUPAC Name (2S,5S,8S,11S)-2-((1H-imidazol-4-yl)methyl)-11-(3-amino-3-oxopropyl)-8-(carboxymethyl)-5-isopropyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazatetradecanoic acid
InChI InChI=1S/C22H33N7O9/c1-10(2)18(21(36)28-15(22(37)38)6-12-8-24-9-25-12)29-20(35)14(7-17(32)33)27-19(34)13(26-11(3)30)4-5-16(23)31/h8-10,13-15,18H,4-7H2,1-3H3,(H2,23,31)(H,24,25)(H,26,30)(H,27,34)(H,28,36)(H,29,35)(H,32,33)(H,37,38)/t13-,14-,15-,18-/m0/s1
SMILES O=C(O)[C@H](CC1=CNC=N1)NC([C@H](C(C)C)NC([C@H](CC(O)=O)NC([C@H](CCC(N)=O)NC(C)=O)=O)=O)=O

1: Shrestha S, Paudel P, Seong SH, Min BS, Seo EK, Jung HA, Choi JS. Two new naphthalenic lactone glycosides from Cassia obtusifolia L. seeds. Arch Pharm Res. 2018 Jun 8. doi: 10.1007/s12272-018-1044-0. [Epub ahead of print] PubMed PMID: 29948771.
2: Knox PP, Lukashev EP, Gorokhov VV, Grishanova NP, Paschenko VZ. Hybrid complexes of photosynthetic reaction centers and quantum dots in various matrices: resistance to UV irradiation and heating. Photosynth Res. 2018 Jun 15. doi: 10.1007/s11120-018-0529-5. [Epub ahead of print] PubMed PMID: 29948749.
3: Stefan A, Calonghi N, Schipani F, Dal Piaz F, Sartor G, Hochkoeppler A. Purification of active recombinant human histone deacetylase 1 (HDAC1) overexpressed in Escherichia coli. Biotechnol Lett. 2018 Jun 14. doi: 10.1007/s10529-018-2585-5. [Epub ahead of print] PubMed PMID: 29948514.
4: Song P, Yuan K, Qin T, Zhang K, Ji XJ, Ren L, Guan R, Wen J, Huang H. Metabolomics profiling reveals the mechanism of increased pneumocandin B(0) production by comparing mutant and parent strains. J Ind Microbiol Biotechnol. 2018 Jun 14. doi: 10.1007/s10295-018-2047-z. [Epub ahead of print] PubMed PMID: 29948195.
5: Ebada ME. Essential oils of green cumin and chamomile partially protect against acute acetaminophen hepatotoxicity in rats. An Acad Bras Cienc. 2018 Jun 25:0. doi: 10.1590/0001-3765201820170825. [Epub ahead of print] PubMed PMID: 29947676.
6: Claaßen C, Claaßen MH, Gohl F, Tovar GEM, Borchers K, Southan A. Photoinduced Cleavage and Hydrolysis of o-Nitrobenzyl Linker and Covalent Linker Immobilization in Gelatin Methacryloyl Hydrogels. Macromol Biosci. 2018 Jun 26:e1800104. doi: 10.1002/mabi.201800104. [Epub ahead of print] PubMed PMID: 29947093.
7: Park JK, Coffey NJ, Limoges A, Le A. The Heterogeneity of Lipid Metabolism in Cancer. Adv Exp Med Biol. 2018;1063:33-55. doi: 10.1007/978-3-319-77736-8_3. PubMed PMID: 29946774.
8: Yang Y, Zhang P, Wang Y, Wei S, Zhang L, Wang J, Lu X, Zhou H, Li R, Wen J, Zhou X, Li H, Li K, Zhao Y. Hepatoprotective Effect of San-Cao Granule on Con A-Induced Liver Injury in Mice and Mechanisms of Action Exploration. Front Pharmacol. 2018 Jun 12;9:624. doi: 10.3389/fphar.2018.00624. eCollection 2018. PubMed PMID: 29946260; PubMed Central PMCID: PMC6005824.
9: Sodhi K, Nichols A, Mallick A, Klug RL, Liu J, Wang X, Srikanthan K, Goguet-Rubio P, Nawab A, Pratt R, Lilly MN, Sanabria JR, Xie Z, Abraham NG, Shapiro JI. The Na/K-ATPase Oxidant Amplification Loop Regulates Aging. Sci Rep. 2018 Jun 26;8(1):9721. doi: 10.1038/s41598-018-26768-9. PubMed PMID: 29946187.
10: Jiang M, McMillan M, Davis VA, Kitchens CL. Phase Behavior of Acetylated Cellulose Nanocrystals and Origins of the Cross-hatch Birefringent Texture. Biomacromolecules. 2018 Jun 26. doi: 10.1021/acs.biomac.8b00746. [Epub ahead of print] PubMed PMID: 29944348.
11: Arahal DR, Lucena T, Rodrigo-Torres L, Pujalte MJ. Ruegeria denitrificans sp. nov., a marine bacterium in the family Rhodobacteraceae with the potential ability for cyanophycin synthesis. Int J Syst Evol Microbiol. 2018 Jun 26. doi: 10.1099/ijsem.0.002867. [Epub ahead of print] PubMed PMID: 29944092.
12: Jaarsma D, Blot FGC, Wu B, Venkatesan S, Voogd J, Meijer D, Ruigrok TJH, Gao Z, Schonewille M, De Zeeuw CI. The basal interstitial nucleus (BIN) of the cerebellum provides diffuse ascending inhibitory input to the floccular granule cell layer. J Comp Neurol. 2018 Jun 26. doi: 10.1002/cne.24479. [Epub ahead of print] PubMed PMID: 29943833.
13: Singh AK, Singh S, Tripathi VK, Bissoyi A, Garg G, Rizvi SI. Rapamycin confers neuroprotection against aging-induced oxidative stress, mitochondrial dysfunction and neurodegeneration in old rats via activation of autophagy. Rejuvenation Res. 2018 Jun 26. doi: 10.1089/rej.2018.2070. [Epub ahead of print] PubMed PMID: 29943667.
14: Miller EJ, Gemensky-Metzler AJ, Wilkie DA, Wynne RM, Curto EM, Chandler HL. Effects of grape seed extract, lutein, and fish oil on responses of canine lens epithelial cells in vitro. Am J Vet Res. 2018 Jul;79(7):770-778. doi: 10.2460/ajvr.79.7.770. PubMed PMID: 29943637.
15: Davoudmanesh S, Mosaabadi JM. Investigation of the effect of homocysteinylation of substance P on its binding to the NK1 receptor using molecular dynamics simulation. J Mol Model. 2018 Jun 26;24(7):177. doi: 10.1007/s00894-018-3695-7. PubMed PMID: 29943287.
16: Kou L, Du M, Liu P, Zhang B, Zhang Y, Yang P, Shang M, Wang X. Anti-Diabetic and Anti-Nephritic Activities of Grifola frondosa Mycelium Polysaccharides in Diet-Streptozotocin-Induced Diabetic Rats Via Modulation on Oxidative Stress. Appl Biochem Biotechnol. 2018 Jun 26. doi: 10.1007/s12010-018-2803-6. [Epub ahead of print] PubMed PMID: 29943275.
17: Chen Y, Huang Q, Liu W, Zhu Q, Cui CP, Xu L, Guo X, Wang P, Liu J, Dong G, Wei W, Liu CH, Feng Z, He F, Zhang L. Mutually exclusive acetylation and ubiquitylation of the splicing factor SRSF5 control tumor growth. Nat Commun. 2018 Jun 25;9(1):2464. doi: 10.1038/s41467-018-04815-3. PubMed PMID: 29942010.
18: Jin J, Richardson L, Sheller-Miller S, Zhong N, Menon R. Oxidative stress induces p38MAPK-dependent senescence in the feto-maternal interface cells. Placenta. 2018 Jul;67:15-23. doi: 10.1016/j.placenta.2018.05.008. Epub 2018 May 17. PubMed PMID: 29941169.
19: Zahoor M, Shafiq S, Ullah H, Sadiq A, Ullah F. Isolation of quercetin and mandelic acid from Aesculus indica fruit and their biological activities. BMC Biochem. 2018 Jun 26;19(1):5. doi: 10.1186/s12858-018-0095-7. PubMed PMID: 29940844.
20: Avedschmidt S, Schmidt C, Isenschmid D, Kesha K, Moons D, Gupta A. Acetyl Fentanyl: Trends and Concentrations in Metro Detroit. J Forensic Sci. 2018 Jun 25. doi: 10.1111/1556-4029.13840. [Epub ahead of print] PubMed PMID: 29940698.

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