Abiraterone- CAS 154229-19-3

CAS No.: 154229-19-3

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Abiraterone,154229-19-3
Product Details
For research use only. Not Intended for Therapeutic Use!
Cat No:A000733
Synonyms:

154229-19-3; (3beta)-17-(3-pyridinyl)-androsta-5,16-dien-3-ol; 17-(3-Pyridyl)androsta-5,16-dien-3beta-ol; CB 7598; CB-7598

Molecular Formula:

C24H31NO

Molecular Weight:349.5
Description:Abiraterone  (CAS 154229-19-3), also known as CB7598, is the active metabolite of abiraterone acetate, which is an orally active acetate ester of the steroidal compound abiraterone with antiandrogen activity. Abiraterone acetate was approved by the U.S.
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Abiraterone  (CAS 154229-19-3), also known as CB7598, is the active metabolite of abiraterone acetate, which is an orally active acetate ester of the steroidal compound abiraterone with antiandrogen activity. Abiraterone acetate was approved by the U.S. Food and Drug Administration (FDA) in April 2011. Abiraterone inhibits the enzymatic activity of steroid 17alpha-monooxygenase (17alpha-hydrolase/C17,20 lyase complex), a member of the cytochrome p450 family that catalyzes the 17alpha-hydroxylation of steroid intermediates involved in testosterone synthesis. Administration of this agent may suppress testosterone production by both the testes and the adrenals to castrate-range levels.

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