Abacavir sulfate

  • CAT Number: I013894
  • CAS Number: 188062-50-2
  • Molecular Formula: C₁₄H₁₈N₆O
  • Molecular Weight: 286.33
  • Purity: ≥95%
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Abacavir sulfate (Cat. No: I013894) is the sulfate of the antiviral drug abacavir, and its pharmacological effect is the same as that of abacavir. It is a nucleoside reverse transcriptase inhibitor with anti-HIV-1 virus activity. It works mainly by inhibiting HIV reverse transcriptase, causing chain scission, and further preventing virus replication.

Catalog Number I013894
CAS Number 188062-50-2
Molecular Formula


Purity 95%
Target Reverse Transcriptase
Solubility 10 mM in H2O
IUPAC Name [(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methanol;sulfuric acid
InChI InChI=1S/2C14H18N6O.H2O4S/c2*15-14-18-12(17-9-2-3-9)11-13(19-14)20(7-16-11)10-4-1-8(5-10)6-21;1-5(2,3)4/h2*1,4,7-10,21H,2-3,5-6H2,(H3,15,17,18,19);(H2,1,2,3,4)/t2*8-,10+;/m11./s1

[1]. Charneira C, et al. Reactive aldehyde metabolites from the anti-HIV drug abacavir: amino acid adducts as possible factors in abacavir toxicity. Chem Res Toxicol. 2011 Dec 19;24(12):2129-41.<br>[2]. Hervey PS, et al. Abacavir: a review of its clinical potential in patients with HIV infection. Drugs. 2000 Aug;60(2):447-79.

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