For research use only. Not for therapeutic Use.
AA38-3（Cat No.:I045058）is a selective small-molecule inhibitor of SHP2 (Src homology region 2-containing protein tyrosine phosphatase 2), a critical signaling node in the RAS/MAPK pathway. By targeting SHP2, AA38-3 blocks downstream oncogenic signaling involved in cell proliferation and survival, particularly in cancers driven by receptor tyrosine kinases or RAS mutations. It is a valuable tool for investigating SHP2’s role in tumorigenesis, immune modulation, and resistance to targeted therapies. AA38-3 is used in preclinical studies to explore novel anticancer strategies.
| CAS Number | 65815-76-1 |
| Synonyms | (4-nitrophenyl) piperidine-1-carboxylate |
| Molecular Formula | C12H14N2O4 |
| Purity | ≥95% |
| IUPAC Name | (4-nitrophenyl) piperidine-1-carboxylate |
| InChI | InChI=1S/C12H14N2O4/c15-12(13-8-2-1-3-9-13)18-11-6-4-10(5-7-11)14(16)17/h4-7H,1-3,8-9H2 |
| InChIKey | DHSYPQIMNAYLCG-UHFFFAOYSA-N |
| SMILES | C1CCN(CC1)C(=O)OC2=CC=C(C=C2)[N+](=O)[O-] |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
