For research use only. Not for therapeutic Use.
A-61603（Cat No.:R026118）is a highly selective α1A-adrenergic receptor agonist, used extensively in cardiovascular and neurological research. Its strong affinity for the α1A subtype, with minimal activity at α1B and α1D receptors, allows precise investigation of α1A-mediated physiological responses. A-61603 is known to induce vasoconstriction and increase blood pressure in preclinical models, aiding studies on vascular tone regulation and sympathetic nervous system activity. Additionally, it has been explored for potential neuroprotective and cognitive-enhancing effects. Its receptor specificity makes A-61603 a valuable pharmacological tool for dissecting adrenergic signaling in therapeutic research.
| CAS Number | 107756-30-9 |
| Synonyms | N-[5-(4,5-dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl]methanesulfonamide;hydrobromide |
| Molecular Formula | C14H20BrN3O3S |
| Purity | ≥95% |
| IUPAC Name | N-[5-(4,5-dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl]methanesulfonamide;hydrobromide |
| InChI | InChI=1S/C14H19N3O3S.BrH/c1-21(19,20)17-13-10-3-2-4-11(14-15-7-8-16-14)9(10)5-6-12(13)18;/h5-6,11,17-18H,2-4,7-8H2,1H3,(H,15,16);1H |
| InChIKey | LRFLWCZMTGTUEP-UHFFFAOYSA-N |
| SMILES | CS(=O)(=O)NC1=C(C=CC2=C1CCCC2C3=NCCN3)O.Br |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
