9α-Fluoroprednisolone 17-Valerate

• CAT Number: R029009
• CAS Number: 2802-10-0
• Molecular Formula: C₂₆H₃₅FO₆
• Molecular Weight: 462.55
• Purity: ≥95%
• Synonyms: 9-Fluoro-11β,17,21-trihydroxy-pregna-1,4-diene-3,20-dione 17-valerate; 9-Fluoro-11β,17,21-dihydroxy-pregna-1,4-diene-3,20-dione 17-valerate
• Storage: -20°C
• IUPAC Name: [(8S,9R,10S,11S,13S,14S,17R)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] pentanoate
• InChI: InChI=1S/C26H35FO6/c1-4-5-6-22(32)33-25(21(31)15-28)12-10-18-19-8-7-16-13-17(29)9-11-23(16,2)26(19,27)20(30)14-24(18,25)3/h9,11,13,18-20,28,30H,4-8,10,12,14-15H2,1-3H3/t18-,19-,20-,23-,24-,25-,26-/m0/s1
• InChIKey: XXQFKBZSMIPUMG-WMUQLZIPSA-N
• SMILES: CCCCC(=O)O[C@@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)O)C)C(=O)CO

9α-Fluoroprednisolone 17-valerate（Cat No.:R029009）is a synthetic corticosteroid ester derived from prednisolone, modified with a fluorine atom at the 9α position and a valerate ester at the 17-hydroxyl group. These modifications enhance its anti-inflammatory potency and lipid solubility, improving skin absorption when used topically. It is commonly applied in the treatment of inflammatory and allergic skin conditions such as eczema, psoriasis, and dermatitis. The compound exerts its effects by inhibiting inflammatory mediators and immune responses. Due to its strength, careful usage is advised to minimize systemic absorption and potential adverse effects.