9-Hydroxy Benzopyrene

• CAT Number: R047701
• CAS Number: 17573-21-6
• Molecular Formula: C20H12O
• Molecular Weight: 268.315
• Purity: ≥95%
• Synonyms: Benzo[a]pyren-9-ol; 9-Hydroxybenzo[a]pyrene
• Storage: -20°C
• IUPAC Name: benzo[a]pyren-9-ol
• InChI: InChI=1S/C20H12O/c21-16-8-6-14-10-15-5-4-12-2-1-3-13-7-9-17(18(14)11-16)20(15)19(12)13/h1-11,21H
• InChIKey: OBBBXCAFTKLFGZ-UHFFFAOYSA-N
• SMILES: C1=CC2=C3C(=C1)C=CC4=C3C(=CC5=C4C=C(C=C5)O)C=C2

9-Hydroxy benzopyrene is a metabolite of benzopyrene, a polycyclic aromatic hydrocarbon found in tobacco smoke, grilled meats, and other combustion processes. This hydroxylated derivative is formed through the action of cytochrome P450 enzymes in the liver. It is a highly reactive compound that can form DNA adducts and contribute to the carcinogenic effects of benzopyrene. Research on 9-hydroxy benzopyrene focuses on its genotoxicity, metabolism, and role in the initiation and progression of cancer.