8-Oxoepiberberine

• CAT Number: I017070
• CAS Number: 19716-60-0
• Molecular Formula: C20H17NO5
• Molecular Weight: 351.35
• Purity: ≥95%
• Synonyms: 16,17-dimethoxy-5,7-dioxa-1-azapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),9,12,14,16,18-heptaen-2-one
• InChI: InChI=1S/C20H17NO5/c1-23-16-8-11-5-6-21-14(13(11)9-17(16)24-2)7-12-3-4-15-19(26-10-25-15)18(12)20(21)22/h3-4,7-9H,5-6,10H2,1-2H3
• InChIKey: PJTYPIGQKDTERS-UHFFFAOYSA-N
• SMILES: COC1=C(C=C2C(=C1)CCN3C2=CC4=C(C3=O)C5=C(C=C4)OCO5)OC

8-Oxoepiberberine(CAT: I017070) is a naturally occurring protoberberine alkaloid derivative, structurally related to epiberberine, a bioactive isoquinoline alkaloid found in medicinal plants such as Berberis and Coptis species. The addition of an 8-oxo functional group modifies its electronic and structural properties, potentially enhancing biological activity. Preliminary studies suggest that 8-Oxoepiberberine may exhibit antimicrobial, antioxidant, and anticancer activities, making it a promising candidate for pharmacological research. It serves as a valuable compound for investigating alkaloid biosynthesis, structure–activity relationships, and therapeutic potential of protoberberine derivatives in infection, metabolic regulation, and oncology.