8-amino-4,5-dihydro-1H-benzo[b]azepin-2(3H)-one

• CAT Number: L026205
• CAS Number: 22246-76-0
• Molecular Formula: C10H12N2O
• Molecular Weight: 176.21
• Purity: ≥95%
• IUPAC Name: 8-amino-1,3,4,5-tetrahydro-1-benzazepin-2-one
• InChI: InChI=1S/C10H12N2O/c11-8-5-4-7-2-1-3-10(13)12-9(7)6-8/h4-6H,1-3,11H2,(H,12,13)
• InChIKey: XRJMPABWIZHNQA-UHFFFAOYSA-N
• SMILES: C1CC2=C(C=C(C=C2)N)NC(=O)C1

8-Amino-4,5-dihydro-1H-benzo[b]azepin-2(3H)-one(CAT: L026205) is a nitrogen-containing heterocycle featuring a seven-membered azepinone ring fused to a benzene ring, with an amino group at the 8-position. This scaffold is structurally related to biologically active compounds, making it valuable in drug discovery and medicinal chemistry. The compound’s lactam (cyclic amide) and primary amine functionalities offer multiple points for derivatization, facilitating the synthesis of analogs for CNS-active agents, enzyme inhibitors, and receptor modulators. Its conformational flexibility and potential to engage in hydrogen bonding make it a promising building block for structure–activity relationship (SAR) studies and pharmaceutical lead optimization