7,8-Dihydroxyflavone

• CAT Number: R058721
• CAS Number: 38183-03-8
• Molecular Formula: C15H10O4
• Molecular Weight: 254.24
• Purity: ≥95%
• Synonyms: 7,8-Dihydroxy-2-phenyl-4H-chromen-4-one; 7,8-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one
• Target: Trk
• Solubility: Soluble in DMSO > 10 mM
• Storage: Store at +4C
• IUPAC Name: 7,8-dihydroxy-2-phenylchromen-4-one
• InChI: InChI=1S/C15H10O4/c16-11-7-6-10-12(17)8-13(19-15(10)14(11)18)9-4-2-1-3-5-9/h1-8,16,18H
• InChIKey: COCYGNDCWFKTMF-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C(=C(C=C3)O)O

7,8-Dihydroxyflavone (Cat No.:R058721) is a naturally occurring flavone compound found in certain plants, known for its potent neuroprotective and therapeutic properties. Structurally, it features a flavone backbone with hydroxyl groups at the 7 and 8 positions, contributing to its antioxidant activity. 7,8-DHF acts as a selective agonist of the TrkB receptor, mimicking brain-derived neurotrophic factor (BDNF), and promotes neuronal survival, growth, and synaptic plasticity. It has been studied for its potential in treating neurodegenerative disorders such as Alzheimer’s, Parkinson’s, and depression, and is widely used in neuroscience research and drug development.