7-(Trifluoromethyl)-2,3-dihydroinden-1-one

• CAT Number: R073810
• CAS Number: 1003048-68-7
• PubChem Substance ID: 22754140
• Molecular Formula: C10H7F3O
• Molecular Weight: 200.16
• Purity: ≥95%
• IUPAC Name: 7-(trifluoromethyl)-2,3-dihydroinden-1-one
• InChI: InChI=1S/C10H7F3O/c11-10(12,13)7-3-1-2-6-4-5-8(14)9(6)7/h1-3H,4-5H2
• InChIKey: RHHGHWBHOQXKNZ-UHFFFAOYSA-N
• SMILES: C1CC(=O)C2=C1C=CC=C2C(F)(F)F

7-(Trifluoromethyl)-2,3-dihydroinden-1-one（Cat No.:R073810）is a fluorinated bicyclic ketone featuring a trifluoromethyl group at the 7-position of the indanone framework. This compound combines a 2,3-dihydroindene core with a reactive ketone functional group, making it a valuable intermediate in organic and medicinal chemistry. The trifluoromethyl group enhances metabolic stability, lipophilicity, and bioactivity, often used to improve pharmacokinetic properties in drug candidates. Its rigid, fused ring system and electron-withdrawing substituent support diverse reactivity, including nucleophilic additions and cyclizations. This molecule is frequently employed in synthesizing fluorinated analogs for pharmaceutical and agrochemical applications.