7-TFA-ap-7-Deaza-dA（Cat No.:I044611）is a synthetic nucleotide analog derived from 7-deaza-2′-deoxyadenosine, in which the purine nitrogen at position 7 is replaced by a carbon, enhancing stability in chemical and enzymatic processes. This analog is modified at the sugar or phosphate backbone with 7-trifluoroacetyl protection (7-TFA) and an ap linker, making it valuable in oligonucleotide synthesis, especially for studying DNA-protein interactions and epigenetic regulation. Its altered electronic structure reduces hydrogen bonding and base pairing ambiguity, improving base discrimination in research involving mutagenesis, nucleic acid therapeutics, and biochemical probe development.