For research use only. Not for therapeutic Use.
7-Iodo-2′,3′-dideoxy-7-deazaadenosine（Cat No.:I044739）is a synthetic nucleoside analog structurally modified at the 7-position with iodine and lacking hydroxyl groups at the 2′ and 3′ positions. This compound mimics adenosine while exhibiting enhanced chemical stability and altered base-pairing properties, making it useful in antiviral and anticancer research. It is particularly valuable in studying nucleoside metabolism, enzyme inhibition, and nucleic acid interactions. The 7-deaza modification reduces tautomerism and increases binding specificity, supporting its application in the development of novel therapeutic agents and oligonucleotide-based technologies.
| CAS Number | 114748-70-8 |
| Synonyms | [(2S,5R)-5-(4-amino-5-iodopyrrolo[2,3-d]pyrimidin-7-yl)oxolan-2-yl]methanol |
| Molecular Formula | C11H13IN4O2 |
| Purity | ≥95% |
| IUPAC Name | [(2S,5R)-5-(4-amino-5-iodopyrrolo[2,3-d]pyrimidin-7-yl)oxolan-2-yl]methanol |
| InChI | InChI=1S/C11H13IN4O2/c12-7-3-16(8-2-1-6(4-17)18-8)11-9(7)10(13)14-5-15-11/h3,5-6,8,17H,1-2,4H2,(H2,13,14,15)/t6-,8+/m0/s1 |
| InChIKey | OEZWDZXBBPSXGY-POYBYMJQSA-N |
| SMILES | C1C[C@@H](O[C@@H]1CO)N2C=C(C3=C(N=CN=C32)N)I |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
