7-Ethoxyresorufin

• CAT Number: R002120
• CAS Number: 5725-91-7
• Molecular Formula: C14H11NO3
• Molecular Weight: 241.24
• Purity: ≥95%
• Synonyms: 7-ethoxyphenoxazin-3-one
• InChI: InChI=1S/C14H11NO3/c1-2-17-10-4-6-12-14(8-10)18-13-7-9(16)3-5-11(13)15-12/h3-8H,2H2,1H3
• InChIKey: CRCWUBLTFGOMDD-UHFFFAOYSA-N
• SMILES: CCOC1=CC2=C(C=C1)N=C3C=CC(=O)C=C3O2

7-Ethoxyresorufin（Cat No.:R002120）is a fluorogenic substrate widely used to study cytochrome P450 enzyme activity, particularly CYP1A1 and CYP1A2 isoforms involved in xenobiotic metabolism. Upon enzymatic O-deethylation, it is converted into resorufin, a highly fluorescent product that enables sensitive detection in kinetic assays. This property makes 7-ethoxyresorufin a key probe in drug metabolism, toxicology, and environmental research. Researchers use it to evaluate enzyme induction, inhibition, and pollutant effects on metabolic pathways. Its specificity and strong signal-to-noise ratio support high-throughput screening and mechanistic enzymology studies.