For research use only. Not for therapeutic Use.
7-Deaza-2′,3′-dideoxyguanosine（Cat No.:I044610）is a synthetic guanosine analog in which the nitrogen at position 7 of the purine ring is replaced by carbon (7-deaza modification), and the 2′ and 3′ hydroxyl groups on the ribose are absent (dideoxy modification). This structural alteration enhances base-pairing specificity and resistance to enzymatic degradation. It is commonly used in antiviral research, nucleic acid chemistry, and as a chain terminator in DNA synthesis due to its inability to form phosphodiester bonds. The compound supports studies in RNA biology, mutagenesis, and nucleic acid-based therapeutic development.
| CAS Number | 111869-49-9 |
| Synonyms | 2-amino-7-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-3H-pyrrolo[2,3-d]pyrimidin-4-one |
| Molecular Formula | C11H14N4O3 |
| Purity | ≥95% |
| IUPAC Name | 2-amino-7-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-3H-pyrrolo[2,3-d]pyrimidin-4-one |
| InChI | InChI=1S/C11H14N4O3/c12-11-13-9-7(10(17)14-11)3-4-15(9)8-2-1-6(5-16)18-8/h3-4,6,8,16H,1-2,5H2,(H3,12,13,14,17)/t6-,8+/m0/s1 |
| InChIKey | IRKZBFORRGBSAO-POYBYMJQSA-N |
| SMILES | C1C[C@@H](O[C@@H]1CO)N2C=CC3=C2N=C(NC3=O)N |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
