7-Amino-3-cephem-4-carboxylic Acid

• CAT Number: R047009
• CAS Number: 36923-17-8
• Molecular Formula: C7H8N2O3S
• Molecular Weight: 200.21
• Purity: ≥95%
• Synonyms: (6R-trans)-7-Amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; (6R,7R)-7-Amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid
• Storage: -20°C
• IUPAC Name: (6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• InChI: InChI=1S/C7H8N2O3S/c8-4-5(10)9-3(7(11)12)1-2-13-6(4)9/h1,4,6H,2,8H2,(H,11,12)/t4-,6-/m1/s1
• InChIKey: RJFPBECTFIUTHB-INEUFUBQSA-N
• SMILES: C1C=C(N2C(S1)C(C2=O)N)C(=O)O

7-Amino-3-cephem-4-carboxylic acid (Cat No.: R047009) is a core β-lactam compound and key intermediate in the synthesis of cephalosporin antibiotics. With a cephem nucleus, it features a four-membered β-lactam ring fused to a six-membered dihydrothiazine ring, an amino group at position 7, and a carboxylic acid at position 4. This structure enables modification at multiple sites to generate various semi-synthetic cephalosporins with tailored antimicrobial properties. 7-ACA is crucial in pharmaceutical manufacturing and is produced via enzymatic or fermentation-based methods.