• CAT Number: I021009
  • CAS Number: 5539-66-2
  • Molecular Formula: C15H10O4
  • Molecular Weight: 254.24
  • Purity: 98%
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1-Hydroxy-8-methoxyanthracene-9,10-dione (Cat No.: I021009), also known as 6PGD-IN-S3, is a ketone derivative and is mainly used as an intermediate in organic synthesis. If you need, please contact us in time, and we will reply to you as soon as possible within 24 hours.

Catalog Number I021009
CAS Number 5539-66-2

6PGD-IN-S3; 6PGD Inhibitor S3; S3; Danthron methyl derivative;

Molecular Formula


Purity 98
Solubility Soluble in DMSO
Storage Sealed in dry,Room Temperature
IUPAC Name 1-hydroxy-8-methoxyanthracene-9,10-dione
InChI InChI=1S/C15H10O4/c1-19-11-7-3-5-9-13(11)15(18)12-8(14(9)17)4-2-6-10(12)16/h2-7,16H,1H3

1: Elf S, Lin R, Xia S, Pan Y, Shan C, Wu S, Lonial S, Gaddh M, Arellano ML, Khoury HJ, Khuri FR, Lee BH, Boggon TJ, Fan J, Chen J. Targeting 6-phosphogluconate dehydrogenase in the oxidative PPP sensitizes leukemia cells to antimalarial agent dihydroartemisinin. Oncogene. 2017 Jan 12;36(2):254-262. doi: 10.1038/onc.2016.196. Epub 2016 Jun 6. PubMed PMID: 27270429; PubMed Central PMCID: PMC5464402.
2: Lin R, Elf S, Shan C, Kang HB, Ji Q, Zhou L, Hitosugi T, Zhang L, Zhang S, Seo JH, Xie J, Tucker M, Gu TL, Sudderth J, Jiang L, Mitsche M, DeBerardinis RJ, Wu S, Li Y, Mao H, Chen PR, Wang D, Chen GZ, Hurwitz SJ, Lonial S, Arellano ML, Khoury HJ, Khuri FR, Lee BH, Lei Q, Brat DJ, Ye K, Boggon TJ, He C, Kang S, Fan J, Chen J. 6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling. Nat Cell Biol. 2015 Nov;17(11):1484-96. doi: 10.1038/ncb3255. Epub 2015 Oct 19. Review. PubMed PMID: 26479318; PubMed Central PMCID: PMC4628560.

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