6PGD-IN-S3

  • CAT Number: I021009
  • CAS Number: 5539-66-2
  • Molecular Formula: C15H10O4
  • Molecular Weight: 254.24
  • Purity: 98%
Inquiry Now

1-Hydroxy-8-methoxyanthracene-9,10-dione (Cat No.: I021009), also known as 6PGD-IN-S3, is a ketone derivative and is mainly used as an intermediate in organic synthesis. If you need, please contact us in time, and we will reply to you as soon as possible within 24 hours.

Catalog Number I021009
CAS Number 5539-66-2
Synonyms

6PGD-IN-S3; 6PGD Inhibitor S3; S3; Danthron methyl derivative;

Molecular Formula

C15H10O4

Purity 98
Solubility Soluble in DMSO
Storage Sealed in dry,Room Temperature
IUPAC Name 1-hydroxy-8-methoxyanthracene-9,10-dione
InChI InChI=1S/C15H10O4/c1-19-11-7-3-5-9-13(11)15(18)12-8(14(9)17)4-2-6-10(12)16/h2-7,16H,1H3
InChIKey QWZMLZHLNDNLAD-UHFFFAOYSA-N
SMILES COC1=CC=CC2=C1C(=O)C3=C(C2=O)C=CC=C3O
Reference

1: Elf S, Lin R, Xia S, Pan Y, Shan C, Wu S, Lonial S, Gaddh M, Arellano ML, Khoury HJ, Khuri FR, Lee BH, Boggon TJ, Fan J, Chen J. Targeting 6-phosphogluconate dehydrogenase in the oxidative PPP sensitizes leukemia cells to antimalarial agent dihydroartemisinin. Oncogene. 2017 Jan 12;36(2):254-262. doi: 10.1038/onc.2016.196. Epub 2016 Jun 6. PubMed PMID: 27270429; PubMed Central PMCID: PMC5464402.
2: Lin R, Elf S, Shan C, Kang HB, Ji Q, Zhou L, Hitosugi T, Zhang L, Zhang S, Seo JH, Xie J, Tucker M, Gu TL, Sudderth J, Jiang L, Mitsche M, DeBerardinis RJ, Wu S, Li Y, Mao H, Chen PR, Wang D, Chen GZ, Hurwitz SJ, Lonial S, Arellano ML, Khoury HJ, Khuri FR, Lee BH, Lei Q, Brat DJ, Ye K, Boggon TJ, He C, Kang S, Fan J, Chen J. 6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling. Nat Cell Biol. 2015 Nov;17(11):1484-96. doi: 10.1038/ncb3255. Epub 2015 Oct 19. Review. PubMed PMID: 26479318; PubMed Central PMCID: PMC4628560.

Request a Quote

Contact Us at MuseChem

We are committed to providing you with reliable, cost-effective solutions for your chemical needs, while ensuring your safety and comfort. Our team of experts is always available to answer your questions and help you navigate the complexities of the chemical industry.

Whether you're looking for a specific product or need help with a custom synthesis project, we're here to help you discover a new world of chemical possibilities. Contact us today to learn more about how we can assist you with all of your chemical needs.

Our goal is to make the process of ordering chemicals as seamless and hassle-free as possible. Let us know how we can assist you, and we'll get back to you as soon as possible. We look forward to hearing from you!