6-Methoxydihydrosanguinarine

• CAT Number: R066377
• CAS Number: 72401-54-8
• Molecular Formula: C21H17NO5
• Molecular Weight: 363.36
• Purity: ≥95%
• Synonyms: 23-methoxy-24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.02,10.04,8.014,22.017,21]tetracosa-1(13),2,4(8),9,11,14(22),15,17(21)-octaene
• InChI: InChI=1S/C21H17NO5/c1-22-19-13(4-3-11-7-16-17(8-14(11)19)26-9-25-16)12-5-6-15-20(27-10-24-15)18(12)21(22)23-2/h3-8,21H,9-10H2,1-2H3
• InChIKey: MHPDDMNAUJQRSW-UHFFFAOYSA-N
• SMILES: CN1C(C2=C(C=CC3=C2OCO3)C4=C1C5=CC6=C(C=C5C=C4)OCO6)OC

6-Methoxydihydrosanguinarine（Cat No.:R066377）is a benzophenanthridine alkaloid derivative primarily found in plants of the Papaveraceae family, such as Macleaya cordata. It exhibits a range of biological activities, including anticancer, antimicrobial, and anti-inflammatory effects. This compound is known to induce apoptosis and inhibit proliferation in cancer cells by targeting key regulatory pathways like NF-κB and caspase activation. Its antimicrobial properties extend to both Gram-positive and Gram-negative bacteria. The methoxy substitution enhances its bioavailability and pharmacological potency, making 6-methoxydihydrosanguinarine a promising candidate for natural therapeutic development in infectious and oncologic diseases.