6/'-Iodoresiniferatoxin

• CAT Number: I010273
• CAS Number: 335151-55-8
• Molecular Formula: C37H39IO9
• Molecular Weight: 754.60
• Purity: ≥95%
• Synonyms: Alternative Name: 6/’-IRTX
• Target: Neuronal Signaling
• Solubility: Soluble in ethanol and in DMSO
• Storage: Desiccate at -20C
• IUPAC Name: [(1R,2R,6R,10S,11R,15R,17R)-13-benzyl-6-hydroxy-4,17-dimethyl-5-oxo-15-prop-1-en-2-yl-12,14,18-trioxapentacyclo[11.4.1.01,10.02,6.011,15]octadeca-3,8-dien-8-yl]methyl 2-(4-hydroxy-2-iodo-5-methoxyphenyl)acetate
• InChI: InChI=1S/C37H39IO9/c1-20(2)35-16-22(4)37-26(33(35)45-36(46-35,47-37)18-23-9-7-6-8-10-23)12-24(17-34(42)30(37)11-21(3)32(34)41)19-44-31(40)14-25-13-29(43-5)28(39)15-27(25)38/h6-13,15,22,26,30,33,39,42H,1,14,16-19H2,2-5H3/t22-,26+,30-,33-,34-,35-,36?,37-/m1/s1
• InChIKey: IITCVPTZKLXSKQ-ZSVIJTOTSA-N
• SMILES: C[C@@H]1C[C@]2([C@H]3[C@H]4[C@]1([C@@H]5C=C(C(=O)[C@]5(CC(=C4)COC(=O)CC6=CC(=C(C=C6I)O)OC)O)C)OC(O3)(O2)CC7=CC=CC=C7)C(=C)C

6′-Iodoresiniferatoxin（Cat No.:I010273）is a potent analog of resiniferatoxin, with the molecular formula C37H39IO9, and functions as an ultrapotent agonist of the transient receptor potential vanilloid 1 (TRPV1) channel. This iodinated derivative is primarily used in neuroscience and pain research to study nociception and sensory neuron activity. By activating TRPV1 receptors, it induces calcium influx and neuronal desensitization, leading to long-lasting analgesic effects. Its high potency and selectivity make it valuable for investigating TRPV1-mediated pathways. Due to its strong bioactivity, it must be handled with extreme caution under controlled laboratory conditions.