6-(Chloromethyl)uracil

• CAT Number: M084029
• CAS Number: 18592-13-7
• Molecular Formula: C5H5ClN2O2
• Molecular Weight: 160.56
• Purity: ≥95%
• Storage: Desiccate at RT
• IUPAC Name: 6-(chloromethyl)-1H-pyrimidine-2,4-dione
• InChI: InChI=1S/C5H5ClN2O2/c6-2-3-1-4(9)8-5(10)7-3/h1H,2H2,(H2,7,8,9,10)
• InChIKey: VCFXBAPEXBTNEA-UHFFFAOYSA-N
• SMILES: C1=C(NC(=O)NC1=O)CCl

6-(Chloromethyl)uracil（Cat No.:M084029）is a halogenated derivative of uracil, a naturally occurring pyrimidine base found in RNA. Featuring a chloromethyl group at the 6-position, this compound is a valuable intermediate in the synthesis of nucleoside analogs and other bioactive molecules. Its reactive chloromethyl moiety enables alkylation reactions, making it useful in medicinal chemistry for developing antiviral and anticancer agents. Additionally, 6-(Chloromethyl)uracil is employed in structure-activity relationship (SAR) studies to explore modifications of nucleobases, offering insights into DNA/RNA interactions and molecular recognition in drug design.