6-Chloro-pyrimidine-2,4-diamine

• CAT Number: R003058
• CAS Number: 156-83-2
• Molecular Formula: C4H5ClN4
• Molecular Weight: 144.56
• Purity: ≥95%
• Synonyms: 6-Chloro-pyrimidine-2,4-diyldiamine, 4-Chloro-2,6-diaminopyrimidine; NSC 8818
• Storage: -20°C
• IUPAC Name: 6-chloropyrimidine-2,4-diamine
• InChI: InChI=1S/C4H5ClN4/c5-2-1-3(6)9-4(7)8-2/h1H,(H4,6,7,8,9)
• InChIKey: QJIUMVUZDYPQRT-UHFFFAOYSA-N
• SMILES: C1=C(N=C(N=C1Cl)N)N

6-Chloropyrimidine-2,4-diamine (Cat No.: R003058) is a heterocyclic organic compound featuring a pyrimidine ring substituted with amino groups at the 2 and 4 positions and a chlorine atom at the 6 position. It serves as a versatile intermediate in the synthesis of pharmaceuticals, agrochemicals, and kinase inhibitors. The electron-withdrawing chlorine atom enhances its reactivity in nucleophilic aromatic substitution reactions, allowing functionalization at the 6-position. This compound is valuable in medicinal chemistry for designing bioactive molecules targeting various biological pathways.