6-Chloro-3-methyluracil

• CAT Number: R017706
• CAS Number: 4318-56-3
• Molecular Formula: C5H5ClN2O2
• Molecular Weight: 160.56
• Purity: ≥95%
• Synonyms: 3-Methyl-6-chlorouracil; 6-Chloro-3-methylpyrimidine-2,4(1H,3H)-dione; 6-Chloro-3-methylpyrimidine-2,4-dione; 6-Chloro-3-methyluracil; 6-Chloro-3-methyl-2,4(1H,3H)-pyrimidinedione
• Storage: Store at +4C
• IUPAC Name: 6-chloro-3-methyl-1H-pyrimidine-2,4-dione
• InChI: InChI=1S/C5H5ClN2O2/c1-8-4(9)2-3(6)7-5(8)10/h2H,1H3,(H,7,10)
• InChIKey: SGLXGFAZAARYJY-UHFFFAOYSA-N
• SMILES: CN1C(=O)C=C(NC1=O)Cl

6-Chloro-3-methyluracil(CAT: R017706) is a halogenated pyrimidine derivative structurally related to uracil, featuring a chlorine atom at the 6-position and a methyl group at the 3-position. This compound is commonly used as an intermediate in pharmaceutical synthesis, especially in the development of antiviral, anticancer, and anti-inflammatory agents. Its electron-withdrawing chloro group enhances reactivity for nucleophilic substitution, enabling further functionalization in heterocyclic chemistry. Additionally, 6-chloro-3-methyluracil serves as a core scaffold in nucleobase analog research and synthesis of bioactive small molecules. Its utility in medicinal chemistry makes it valuable for structure–activity relationship (SAR) studies and lead optimization processes.