6-Bromo-4-chloroquinazoline

• CAT Number: L030087
• CAS Number: 38267-96-8
• Molecular Formula: C8H4BrClN2
• Molecular Weight: 243.49
• Purity: ≥95%
• IUPAC Name: 6-bromo-4-chloroquinazoline
• InChI: InChI=1S/C8H4BrClN2/c9-5-1-2-7-6(3-5)8(10)12-4-11-7/h1-4H
• InChIKey: JFJNDMNYNYLFLJ-UHFFFAOYSA-N
• SMILES: C1=CC2=C(C=C1Br)C(=NC=N2)Cl

6-Bromo-4-chloroquinazoline（Cat No.:L030087）is a halogenated heterocyclic compound featuring a quinazoline core substituted with a bromine atom at the 6-position and a chlorine atom at the 4-position. This dual-halogenated structure offers excellent versatility for further functionalization, particularly in cross-coupling reactions such as Suzuki, Buchwald–Hartwig, or nucleophilic aromatic substitution. It serves as a valuable intermediate in the synthesis of kinase inhibitors and other bioactive molecules, especially in oncology and inflammatory disease research. The quinazoline ring system is a privileged scaffold in medicinal chemistry, contributing to its widespread use in drug discovery and development.