6-Bromo-1-methylindolin-2-one

• CAT Number: L022279
• CAS Number: 897957-06-1
• Molecular Formula: C9H8BrNO
• Molecular Weight: 226.07
• Purity: ≥95%
• IUPAC Name: 6-bromo-1-methyl-3H-indol-2-one
• InChI: InChI=1S/C9H8BrNO/c1-11-8-5-7(10)3-2-6(8)4-9(11)12/h2-3,5H,4H2,1H3
• InChIKey: UUQLZGHQLZAFHD-UHFFFAOYSA-N
• SMILES: CN1C(=O)CC2=C1C=C(C=C2)Br

6-Bromo-1-methylindolin-2-one（Cat No.:L022279）is a brominated indolinone derivative featuring a methyl group at the nitrogen (1-position) and a bromine atom at the 6-position on the aromatic ring. The indolin-2-one core is a privileged scaffold in medicinal chemistry, often found in kinase inhibitors and other bioactive molecules. The bromine substituent provides a reactive site for cross-coupling reactions, enabling structural diversification through Suzuki or Heck coupling. Its rigid, partially saturated bicyclic structure offers favorable pharmacokinetic properties, making it a valuable intermediate in the synthesis of pharmaceuticals, agrochemicals, and functional organic materials.