6-((2,5-Dioxopyrrolidin-1-yl)oxy)-6-oxohexanoic acid

• CAT Number: L048748
• CAS Number: 118380-07-7
• Molecular Formula: C10H13NO6
• Molecular Weight: 243.21
• Purity: ≥95%
• IUPAC Name: 6-(2,5-dioxopyrrolidin-1-yl)oxy-6-oxohexanoic acid
• InChI: InChI=1S/C10H13NO6/c12-7-5-6-8(13)11(7)17-10(16)4-2-1-3-9(14)15/h1-6H2,(H,14,15)
• InChIKey: JWUFSYXQWPXFIL-UHFFFAOYSA-N
• SMILES: C1CC(=O)N(C1=O)OC(=O)CCCCC(=O)O

6-((2,5-Dioxopyrrolidin-1-yl)oxy)-6-oxohexanoic acid（Cat No.:L048748）, commonly known as NHS-activated adipic acid, is a reactive ester featuring a hexanoic acid backbone with a terminal carboxylic acid and a 2,5-dioxopyrrolidin-1-yl (N-hydroxysuccinimide or NHS) ester at the other end. This compound is widely used in bioconjugation and peptide synthesis to activate carboxylic acids for efficient coupling with amines, forming stable amide bonds. The NHS ester enhances reactivity and selectivity under mild conditions, making it valuable for labeling biomolecules, surface modification, and crosslinking applications in pharmaceutical, biochemical, and material science research.