(5R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-5-[[(methylsulfonyl)oxy]methyl]-2-oxazolidinone

• CAT Number: R021535
• CAS Number: 174649-09-3
• Molecular Formula: C15H19FN2O6S
• Molecular Weight: 374.38
• Purity: ≥95%
• Synonyms: (R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-5-[[(methylsulfonyl)oxy]methyl]-2-oxazolidinone, Linezolid Related Compound D,
• Storage: -20°C
• IUPAC Name: [(5R)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl methanesulfonate
• InChI: InChI=1S/C15H19FN2O6S/c1-25(20,21)23-10-12-9-18(15(19)24-12)11-2-3-14(13(16)8-11)17-4-6-22-7-5-17/h2-3,8,12H,4-7,9-10H2,1H3/t12-/m1/s1
• InChIKey: UCVIKCGVGWBTTI-GFCCVEGCSA-N
• SMILES: CS(=O)(=O)OCC1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCOCC3)F

(5R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-5-[[(methylsulfonyl)oxy]methyl]-2-oxazolidinone(CAT: R021535) is a complex, chiral oxazolidinone derivative with high value in pharmaceutical research and intermediate development. Featuring a fluorinated aryl-morpholine moiety and a methanesulfonate leaving group, it serves as a versatile precursor in the synthesis of bioactive compounds, particularly antibacterial agents. The (5R)-configuration is critical for biological activity in oxazolidinone-based drugs, which often target bacterial ribosomal subunits. The presence of the sulfonate ester enables selective substitution or coupling reactions, facilitating molecular diversification. This compound is ideal for medicinal chemistry programs focused on structure–activity relationship (SAR) exploration, especially in the development of oxazolidinone-derived therapeutics or analogs.