5F-203

• CAT Number: R027948
• CAS Number: 260443-89-8
• Molecular Formula: C14H11FN2S
• Molecular Weight: 258.31
• Purity: ≥95%
• Synonyms: 4-(5-fluoro-1,3-benzothiazol-2-yl)-2-methylaniline
• InChI: InChI=1S/C14H11FN2S/c1-8-6-9(2-4-11(8)16)14-17-12-7-10(15)3-5-13(12)18-14/h2-7H,16H2,1H3
• InChIKey: IFWLHIIUGSEKKE-UHFFFAOYSA-N
• SMILES: CC1=C(C=CC(=C1)C2=NC3=C(S2)C=CC(=C3)F)N

5F-203（Cat No.:R027948）is a potent aryl hydrocarbon receptor (AhR) ligand and selective anticancer agent that functions through DNA damage and oxidative stress pathways. Structurally related to benzothiazole derivatives, it selectively targets cancer cells expressing the AhR, leading to cytochrome P450 (CYP1A1) induction, bioactivation, and tumor-specific cytotoxicity. 5F-203 has shown efficacy in breast, ovarian, and gastric cancer models, making it a valuable research tool in oncology. Its unique mechanism—AhR-mediated activation followed by DNA interaction—supports its potential in developing targeted cancer therapies with minimal off-target toxicity.