5-(Trifluoromethyl)-2-(chloromethyl)-1,3,4-oxadiazole

• CAT Number: R008918
• CAS Number: 723286-98-4
• Molecular Formula: C4H2ClF3N2O
• Molecular Weight: 186.52
• Purity: ≥95%
• Synonyms: 2-Chloromethyl-5-trifluoromethyl-1,3,4-oxadiazole
• Storage: -20°C
• IUPAC Name: 2-(chloromethyl)-5-(trifluoromethyl)-1,3,4-oxadiazole
• InChI: InChI=1S/C4H2ClF3N2O/c5-1-2-9-10-3(11-2)4(6,7)8/h1H2
• InChIKey: GPXSXZGMVOSWMN-UHFFFAOYSA-N
• SMILES: C(C1=NN=C(O1)C(F)(F)F)Cl

5-(Trifluoromethyl)-2-(chloromethyl)-1,3,4-oxadiazole(CAT: R008918) is a fluorinated heterocyclic compound valued as a reactive intermediate in pharmaceutical, agrochemical, and materials research. Featuring a 1,3,4-oxadiazole core substituted with a trifluoromethyl and chloromethyl group, it offers high electrophilicity and tunable reactivity. The trifluoromethyl moiety enhances metabolic stability and lipophilicity, while the chloromethyl group enables further derivatization through nucleophilic substitution or cross-coupling reactions.